Fast Car duet – Tracy Chapman & Luke Combs

A Quirky Idea -> Trillion Dollar Nvidia

Source: MIT Technology Review, Oct 2023

Nvidia is now a trillion-dollar company.

At the time it was desperate to find applications for its niche new hardware. “When you invent a new technology, you have to be receptive to crazy ideas,” says Nvidia CEO Jensen Huang. “My state of mind was always to be looking for something quirky, and the idea that neural networks would transform computer science—that was an outrageously quirky idea.”

AI just beat a human test for creativity.

Source: MIT Technology Review, Sep 2023

 

Sex for Healing Trauma

Source: Splice Today, Sep 2023

Our culture is so afraid of sex that we’ve walled it off from healing.

Honest, loving, judgment-free, no performance-anxiety sex is better than any therapy I’ve researched or experienced.

Sex, in the right context of absolute consent and trust, can bring a person back into their body and mind, even soul, in a way that no yoga class can.

Over the years, I’ve had friends and lovers who didn’t realize how much pain they were in until a caring sexual relationship showed them how it felt to be loved.

Perhaps I’m a psychological cuddler.

Image Source: https://www.menshealth.com/sex-women/g36789679/cuddling-positions/

The sex doesn’t always have to be physical. Just showing appreciation for someone else as a sexual being can pour healing ointment on the wounds of trauma.

Real physical closeness is even more powerful. The first time a man realizes he can drop his need to perform in bed and simply take it slow, and enjoy being cared for, is a beautiful thing to experience. It builds his confidence so he’s not so vulnerable to attack. It attracts other women too.

  •  Find someone you like, someone who cares about you.
  • It doesn’t have to be forever.
  • Be open to possibilities.
  • Try not to grasp, and enjoy the moment.

Related Resources:

Cuddle Positions, Stylecaster, March 2019

Cuddle Positions – Every Night

Cuddle Positions – Binky

 

 

Who’s Better at Generating Innovative Ideas, ChatGPT or M.B.A. Students?

Source: MishTalk, Sep 2023
<original research article>

ChatGPT can generate ides far faster than humans. This gives them a huge edge in coming up with a few great ideas. For this study the professors gave ChatGPT and the students the same prompt.

Do LLMs Enhance Productivity in Generating Ideas?

The answer to this question is straightforward. ChatGPT-4 is very efficient at generating ideas. This question does not require much precision to answer. Two hundred ideas can be generated by one human interacting with ChatGPT-4 in about 15 minutes. A human working alone can generate about five ideas in 15 minutes (Girotra et al., 2010). Humans working in groups do even worse. In short, the productivity race between humans and ChatGPT is not even close.

For the focused idea generation task itself, a human using ChatGPT-4 is thus about 40 times more productive than a human working alone.

Chat-GPT generated the best-rated idea in our sample, with an 11% higher purchase probability than the best human idea.

The average quality of the top decile in each of the three pools also follows the same pattern as average quality— seeded Chat-GPT ≻ ChatGPT ≻ Humans.

Overall, we have 400 ideas, with an equal number generated by ChatGPT and humans. In the top 40 ideas (top decile) a full 35 (87.5%) are those generated by ChatGPT.

 

Cyndi Lauper – True Colors

Strategy for Culture Change

Source: COS.IO, Jun 2019

COS’s strategy for culture and behavior change requires five levels of intervention represented by the pyramid above.

These levels are progressive, reflecting the fact that successful implementation of higher levels depends on successful implementation of lower levels.

Infrastructure is the base of the pyramid making behavior change possible.

Asian Glow

Source: Washington Post, Aug 2023

the genetic mutation that causes what is known as alcohol flush reaction.

About 560 million people, or 8 percent of the global population, carry this mutation, with the vast majority being of East Asian descent — hence the nickname for the reaction, “Asian glow” or “Asian flush.”

An estimated 45 percent of East Asians get the “glow” when drinking.

people who experience alcohol flush reaction should drink as little as possible or ideally not at all. The redness and other symptoms may be thought of as a severe warning from the body that alcohol is extremely toxic to this individual, much more so than to many others.

The associated mutation, known as the ALDH2*2 variant, has been linked to a staggering number of diseases in those who consume moderate to large quantities of alcohol.

someone with the ALDH2*2 variant who drinks in moderation — defined as two drinks a day for men and one drink a day for women — has a risk of esophageal cancer 40 to 80 times higher than a person without the mutation who consumes the same amount.

It is a dose-dependent relationship, meaning that more drinks per day translates to an even greater risk. The ALDH2*2 variant does not influence esophageal cancer risk in nondrinkers.

The mutation has also been associated with an increased risk of head and neck cancersgastric cancercoronary artery diseasestroke and osteoporosis in East Asian populations.

People with the ALDH2*2 variant lack a functional enzyme that helps the body break down alcohol. Alcohol is normally metabolized by the body in two steps. One enzyme converts alcohol into acetaldehyde, a compound significantly more toxic to humans than the alcohol itself. A second enzyme then quickly converts acetaldehyde into acetate, a compound that can be safely metabolized by the body.

People with alcohol flush reaction produce a version of the second enzyme, mitochondrial aldehyde dehydrogenase 2 (ALDH2), that has very low activity. This ALDH2 deficiency leads to alcohol not being metabolized normally, and acetaldehyde — essentially, a poison — builds up in the blood.

“Acetaldehyde is classified as a Group 1 carcinogen by the World Health Organization, meaning it has been proven to cause cancer in humans,” said Che-Hong Chen, country director of the Stanford Center for Asian Health Research and Education. “Even with just two cans of beer, the amount of acetaldehyde in their blood is already reaching carcinogenic levels.”

Mathematics Has a Biological Origin

Source: The Conversation, Aug 2023

mathematics is a realisation in symbols of the fundamental nature and creativity of the mind.

Why is arithmetic universally true?

Humans have been making symbols for numbers for more than 5,500 years. More than 100 distinct notation systems are known to have been used by different civilisations, including Babylonian, Egyptian, Etruscan, Mayan and Khmer.

What is mathematics?

Taken together, these four principles structure our perception of the world so that our experience is ordered and cognitively manageable. They are like coloured spectacles that shape and constrain our experience in particular ways.

When we peer through these spectacles at the abstract universe of possibilities, we “see” numbers and arithmetic.

our results show that arithmetic is biologically-based and a natural consequence of how our perception is structured.

Although this structure is shared with other animals, only humans have invented mathematics. It is humanity’s most intimate creation, a realisation in symbols of the fundamental nature and creativity of the mind.

In this sense, mathematics is both invented (uniquely human) and discovered (biologically-based). The seemingly miraculous success of mathematics in the physical sciences hints that our mind and the world are not separate, but part of a common unity.

Paul Graham : Interview

Source: Conversations with Tyler, Aug 2023

GRAHAM: I can tell if people know what they’re talking about when they come and talk about some idea, especially some technical idea. I can tell if they know, if they actually understand [laughs] the idea, or if they just have a reading-the-newspaper level of understanding of the thing.

the way you tell determination is not so much from talking to them as from asking them stories about things that have happened to them. That’s where you can see determination.

it’s what they did in the story, right? … Something went wrong, and instead of giving up, they persevered.

GRAHAM: Well, people should do some work. When I talk to people who are in their teens or early 20s about starting a start-up, I tell them, “Instead of sitting around thinking of start-up ideas, you should be working with other people on projects. Then, you’ll get a start-up idea out of it that you probably never would have thought of, and you’ll get a co-founder too.” I wish people would do more of that. You can get co-founders — just work with people on projects. You just can’t get co-founders instantly. You’ve got to have some patience.

On increasing ambition

COWEN: Why is there not more ambition in the developed world? Say we wanted to boost ambition by 2X. What’s the actual constraint? What stands in the way?

GRAHAM: Boy, what a fabulous question. I wish you’d asked me that an hour ago, so I could have had some time to think about it between now and then.

COWEN: [laughs] You’re clearly good at boosting ambition, so you’re pulling on some lever, right? What is it you do?

GRAHAM: Oh, okay. How do I do it? People are, for various reasons — for multiple reasons — they’re afraid to think really big. There are multiple reasons. One, it seems overreaching. Two, it seems like it would be an awful lot of work. [laughs]

COWEN: How much of what you do is reshuffling their networks? There are people with potential. They’re in semi-average networks —

GRAHAM: Wait. That was such an interesting question. We should talk about that some more because that really is an interesting question. Imagine how amazing it would be if all the ambitious people can be more ambitious. That really is an interesting question. There’s got to be more to it than just the fact that I don’t have to do the work.

COWEN: I think a lot of it is reshuffling networks. You need someone who can identify who should be in a better network. You boost the total size of all networking that goes on, and you make sure those people with potential —

GRAHAM: By reshuffling networks, you mean introducing people to one another?

COWEN: Of course.

GRAHAM: Yes.

COWEN: You pull them away from their old peers, who are not good enough for them, and you bring them into new circles, which will raise their sights.

GRAHAM: You know what we do in YC interviews? We basically start YC, the first 10 minutes of YC is the interview. You see what it’s like to work with people by working with them for 10 minutes, and that’s enough, it turns out.

COWEN: So, you think the 11th minute of an interview has very low value.

GRAHAM: I’ve thought a lot about where the cutoff is. Like, where’s the point? If you made a graph, what’s your probability of changing your mind after minute number N? After minute number one or two, the probability of changing your mind is pretty high. I would say YC interviews could actually be seven minutes instead of ten minutes, but ten minutes is already almost insultingly short, so we kept it at ten. We could have made it seven.

COWEN: I think there’s often a threshold of two, and then another threshold at about seven, and after that, it’s very tough for it to flip.

GRAHAM: Yes. Although that doesn’t mean you’re always right.

COWEN: It could just be, after three hours, you would still be wrong.

GRAHAM: It’s just not going to flip. I didn’t say seven minutes is enough to tell, notice. [laughs] I said seven minutes is the point where you’re probably not going to change your mind.

COWEN: Clearly, from zero to one or two, they get over nerves, or they adjust the sound volume. There are plenty of those stories.

GRAHAM: It’s probably that we misunderstood what they’re working on initially.

COWEN: So, great idea, bad at presenting it?

GRAHAM: No, more like they’re near some idea that we’re familiar with, and we just assume they must be doing that idea. And they say, “Oh, no, no, no, we’re not doing that. We’re doing this.” I’m like, “Oh, okay. Thank goodness.” Then, they get extra points because not only they’re not doing the stupid thing, but they understand that the stupid thing is stupid. They get extra credit for what we were subtracting for it in the past.

COWEN: Very last question. In my view, a life properly lived is learn, learn, learn all the time.

GRAHAM: That’s what Charlie Munger said, right?

COWEN: Paul Graham, thank you very much.

GRAHAM: [laughs] Thank you. Boy, that was so many hard questions.

Related Resource: YCombinator, Feb 2016