Source: Asian Scientist, Jan 2016
Using the analogy of Lego bricks, Negishi described his vision for organic synthesis—he wanted to synthesize complex chemical compounds from basic starting materials in a fuss-free manner, such as how one can build virtually anything from Lego bricks.
… the importance of optimism in scientific research. “This is how I eventually got the Nobel Prize, with eternal optimism. Never get discouraged. Keep working,” he said.